SMILE®-platform used for optogenetics

In close collaboration with the Institute of Quantum Optics (IQO) in Hannover, we were able to demonstrate for the first time that biological cells could be excited using our SMILE®-platform.

In the lab of Prof. Alexander Heisterkamp at NIFE (Niedersächsisches Zentrum für Biomedizintechnik, Implantatforschung und Entwicklung), Dr. Maria Leilani Torres and their team employ fluorescence imaging to visualize calcium fluctuations in living cells.

The cardiomyocytes express a light-sensitive protein called ChR2. The cells were stained with calcium-sensitive dye and are activated when illuminated by SMILE®-platform. The spontaneous electrical activity can be overridden by the illumination pattern.

Using our SMILE®-platform, cell cultures can be stimulated by different illumination patterns.

We are very proud that our microLED platform simplifies research by providing a compact and easy-to-use light source for targeted stimulation of cells with minimal adjustment required compared to other optical systems.

The video shows cardiomyocytes illuminated with vertical light stripe patterns using the SMILE®-platform.

Source: Dr. Maria Leilani Torres, Leibniz University Hannover.

The next generation of µLED technologies

As part of the EU project SMILE in which we are proud to be a project partner, a new generation of µLED technology is being developed.

Professor J. Daniel Prades from the Universitat de Barcelona visited the Quantum Valley Lower Saxony (QVLS) at the Mobile World Congress in Barcelona and gave this exciting interview:

QubeDot at the CS International Conference in Brussels

Our team from QubeDot is very pleased to have been part of the CS International Conference in Brussels.

Jan, our CTO and Co-Founder of QubeDot, has given a talk about µLEDs for structured illumination and the versatility of our SMILE® Technology to address multiple markets.

µLEDs with dimensions of 1 to 50 µm are becoming increasingly interesting driven by the µLED revolution in display technology.

Our µLEDs are in addition also used – among other applications – in biology, optogenetics, microscopy and process metrology.

Do you want to know more about our customized µLEDs?

Here is the link to our solutions:

New housing for SMILE platform

Our µLED arrays are the key to our Structured Micro Illumination Light Engine (SMILE) platform. They enable as a complete system the precise control of every single light pattern.

MicroLED array with 16×16 pixels in new star housing – connected to USB and ready to illuminate your samples.

The new housing allows for an easy integration of the SMILE platform into optical system as it is compatible to 60mm cage systems and offers additional threads.